Parkinson’s Disease

Research Article

Can the Executive Control Network be Used to Diagnose Parkinson’s Disease and as an Efficacy Indicator of Deep Brain Stimulation?

Table 1

Demographics and clinical measures of patients with PD and controls.


Items	CN	PD	T values (χ²)	values
Items	n = 14	n = 23	T values (χ²)	values

Age (years)	63.29 (9.72)	60.91 (12.62)	1.134	0.323
Gender (male/female)	7/7	9/14	0.419	0.517
MMSE	27.86 (1.86)	26.57 (2.37)	1.733	0.092
MoCA	28.71 (1.07)	24.91 (2.39)	5.593	<0.001
HAMA	0.43 (0.51)	5.00 (3.81)	4.436	<0.001
HAMD	0.79 (0.89)	5.26 (4.17)	3.961	<0.001
UPDRS-III	—	39.30 (12.47)	—	—
PDQ-39	—	44.09 (17.29)	—	—

Data are presented as the mean (with standard deviation, SD). Abbreviations: CN, controls; PD, Parkinson’s disease; MMSE, Mini-Mental State Exam; MoCA, Montreal Cognitive Assessment scale; HAMA, Hamilton Anxiety Scale; HAMD, Hamilton Depression Scale; UPDRS-III, Unified Parkinson’s Disease Rating Scale Part III; PDQ-39, the 39-item Parkinson’s Disease Questionnaire. Significant differences were found between the two groups. The values were obtained by using the independent sample t test except for gender (chi-square test).