Research Article
Can the Executive Control Network be Used to Diagnose Parkinson’s Disease and as an Efficacy Indicator of Deep Brain Stimulation?
Table 2
Comparisons of functional connectivity of the brain networks during CN, pre-PD, and post-PD.
| Brain regions | Peak MNI coordinate | Peak T value | Cluster size (mm3) | x | y | z |
| CN > pre-PD | R inferior frontal gyrus | 48 | 24 | 15 | 5.44 | 1269 | L precuneus | −27 | −51 | 36 | 4.79 | 4698 | R precuneus | 21 | −66 | 36 | 6.18 | 5967 | L inferior frontal gyrus | −57 | 6 | 39 | 5.29 | 2430 | R middle frontal gyrus | 36 | 9 | 42 | 5.26 | 2862 | R postcentral gyrus | 24 | −45 | 51 | 5.58 | 1350 | R inferior parietal lobule | 36 | −57 | 36 | 4.72 | 2727 | L cerebellum posterior lobe | −30 | −78 | −45 | 5.09 | 1458 |
| CN > post-PD | L cerebellum posterior lobe | −30 | −78 | −42 | 5.27 | 1107 | R inferior frontal gyrus | 45 | 18 | 18 | 4.11 | 918 | L inferior frontal gyrus | −57 | 6 | 39 | 5.60 | 4509 | L precuneus | −27 | −51 | 36 | 5.13 | 1809 | R middle frontal gyrus | 33 | 3 | 39 | 4.08 | 1377 | R inferior parietal lobule | 39 | −69 | 54 | 4.33 | 1080 |
| Pre-PD < post-PD | Nr | — | — | — | — | — |
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Abbreviations: CN, controls; pre-PD, preoperation Parkinson’s disease; post-PD, postoperation Parkinson’s disease; ECN, executive control network; Nr, no statistically significant differences between brain regions.
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