5-2-1 Criteria: A Simple Screening Tool for Identifying Advanced PD Patients Who Need an Optimization of Parkinson’s Treatment
Table 2
QoL and autonomy for activities of daily living in patients with 5-2-1 criteria (n = 20) vs those with 5-2-1 negative criteria (n = 82).
5-2-1 positive (n = 20)
5-2-1 negative (n = 82)
value
PDQ-39SI
25.6 ± 14
12.1 ± 9.2
<0.0001
Mobility
32.1 ± 22.4
11.7 ± 17.7
<0.0001
Activities of daily living
25.8 ± 15.3
12.1 ± 12
<0.0001
Emotional well-being
29.1 ± 27.5
16.1 ± 18.9
0.014
Stigma
16.8 ± 32.4
6 ± 14.9
0.028
Social support
7.1 ± 16.5
2.5 ± 9.3
0.102
Cognition
22.2 ± 21
14.2 ± 15.8
0.060
Communication
2.9 ± 7.8
2.7 ± 7.7
0.927
Pain and discomfort
52.4 ± 26.6
29.8 ± 20.4
<0.0001
PQ-10
6.1 ± 2
7.1 ± 1.3
0.007
EUROHIS-QOL8
3.5 ± 0.5
3.7 ± 0.4
0.034
Quality of life
3.4 ± 0.9
3.8 ± 0.6
0.024
Health status
3 ± 0.8
3.3 ± 0.7
0.069
Energy
3.6 ± 0.6
3.7 ± 0.6
0.452
Autonomy for ADL
2.9 ± 0.7
3.6 ± 0.6
<0.0001
Self-esteem
3.6 ± 1.2
3.8 ± 0.7
0.313
Social relationships
3.9 ± 0.8
4 ± 0.5
0.657
Economic capacity
3.8 ± 0.6
3.8 ± 0.6
0.968
Habitat
4 ± 0.8
4.1 ± 0.5
0.452
ADLS
73.5 ± 13.1
89.2 ± 9.3
<0.0001
Functional dependency (%)
45
7.3
<0.0001
Chi-squared and Mann–Whitney–Wilcoxon tests were applied. ADLS, Schwab and England Activities of Daily Living Scale; PDQ-39SI, 39-Item Parkinson’s Disease Quality of Life Questionnaire Summary Index.
