Research Article

Analysis of Motor Complication and Relative Factors in a Cohort of Chinese Patients with Parkinson’s Disease

Table 4

The results of motor fluctuations and dyskinesia in different clinical stages.

Total (n = 166)Motor fluctuations (n = 52)χ2 valueDyskinesia (n = 25)χ2 value

Age of onset (n, %)16.625<0.0019.1010.011
 ≤50 years29 (17.47)18 (62.07)9 (31.03)
 51–70 years107 (64.46)29 (27.10)15 (14.02)
 ≥70 years30 (18.07)5 (16.67)1 (3.33)

Duration of diseases40.806<0.00148.692<0.001
 <5 years91 (54.82)11 (12.09)2 (2.20)
 5–10 years59 (35.54)28 (47.46)12 (20.34)
 ≥10 years16 (9.64)13 (81.25)11 (68.75)

Duration of L-dopa treatment (n, %)67.265<0.00146.087<0.001
 ≤2 years98 (59.04)7 (7.12)0 (0.00)
 2–5 years36 (21.69)21 (58.33)11 (30.56)
 5–10 years23 (13.86)17 (73.91)9 (39.13)
 ≥10 years9 (5.41)7 (77.78)5 (55.56)

Modified Hoehn–Yahr stages (n, %)29.030<0.00146.030<0.001
 1–1.551 (30.72)6 (11.76)0 (0.00)
 2–2.576 (45.78)21 (27.63)6 (7.89)
 3-439 (23.50)25 (64.10)19 (48.72)

Daily levodopa dosages (n, %)17.012<0.0016.8800.032
 ≤300 mg49 (29.52)6 (12.24)4 (8.16)
 300–600 mg91 (54.82)31 (34.07)13 (14.29)
 ≥600 mg26 (15.66)15 (57.69)8 (30.77)