Research Article
Ultrasonographic Changes in Brain Hemodynamics in Patients with Parkinson’s Disease and Risk Factors for Cerebrovascular Disease: A Pilot Study
Table 2
Comparison of ultrasound characteristics between the groups (PDvasc x PDnvasc).
| | | Total sample | PDvasc | PDnvasc | -value |
| | Variable | n = 27 | n = 11 | n = 16 | | | Area of SN (cm2) | 0.25 | 0.25 | 0.23 | 0.656 | | Vm after apnea (cm/s) | 49.37 | 45.17 | 52.26 | 0.126 | | RI | 0.55 | 0.59 | 0.51 | 0.050 | | PI | 0.85 | 1.00 | 0.75 | 0.020 | | AI | 0.78 | 0.46 | 1.01 | 0.027 |
| | Altered cVR, n (%) | | | | | | No = AI ≥ 0.70 | 13 (48.1) | 1 (9.10) | 12 (75.0) | 0.001 | | Yes = AI < 0.69 | 14 (51.9) | 10 (90.9) | 4 (25.0) | | | H&Y scale (mean) | 2 | 2.5 | 1.7 | 0.036 | | UPDRSIII (median) | 18 | 19 | 16 | 0.526 |
| | PD phenotype, n (%) | | | | | | Classic | 17 (63) | 5 (45.4) | 12 (75) | 0.223 | | Akinetic-rigid | 10 (37) | 6 (54.6) | 4 (25) | | | MOCA (median) | 22 | 22 | 22.5 | 0.676 |
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SN: substantia nigra. RI: resistance index. PI: pulsatility index. AI: apnea index. cVR: cerebrovascular reactivity.
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