Research Article

Gender Was Associated with Depression but Not with Gastrointestinal Dysfunction in Patients with Parkinson’s Disease

Table 3

Motor symptoms and other nonmotor symptoms in M-PD and FM-PD group (%).

Total PD (n = 186)M-PD (n = 95, 51.08%)FM-PD (n = 91, 48.92%)t/Z/χ2P

Age of motor symptoms onset62.01 ± 9.5662.33 ± 9.9161.68 ± 9.220.4590.647
Type of motor symptom onset (case %)
Tremor92 (49.46%)49 (53.3%)43 (46.7%)0.3480.555
Nontremor94 (50.54%)46 (48.9%)48 (51.1%)
Location of motor symptom onset (case %)
Left88 (47.31%)43 (48.9%)45 (51.1%)4.2470.120
Right84 (45.16%)48 (57.1%)36 (42.9%)
Dual side14 (7.53%)4 (28.6%)10 (71.4%)
Phenotype of motor symptom (case %)
TD52 (27.96%)26 (50.0%)26 (50.0%)0.4580.795
AR47 (25.27%)26 (55.3%)21 (44.7%)
Mixed87 (46.77%)43 (49.4%)44 (50.6%)
H-Y (onstage)2.25 ± 1.052.20 ± 0.952.32 ± 1.15−0.7650.445
UPDRS-I9 (4.5–15)9 (4–15)9.5 (5.25–19.0)−0.8210.413
UPDRS-II14 (7.5–26.5)13 (9–22.5)16 (5.25–32.25)−0.9830.329
UPDRS-III34 (18.5–56.5)32 (17–51.5)40.5 (21.25–65.75)−2.1310.034
UPDRS-IV0 (0–1)0 (0–0)0 (0–3.5)−1.7180.09
PQSI (scores)8 (3–13)8 (4–11)7 (3.25–10.0)−1.6510.10
ESS (scores)5 (1–11.0)6 (1.5–11.0)9 (1.0–15.0)−0.7960.427
RLS2.0 (0.0–5.0)1.0 (0.0–5.0)3.0 (0.0–6.0)0.0470.962
RBD44 (23.6%)17 (18.9%)26 (28.6%)2.00.157
HAMA (scores)3.0 (1.0–8.0)3.0 (0.0–8.0)5.0 (0.0–15.0)−1.9180.057
HAMD (scores)5.0 (1–13.0)5.0 (1.5–10.0)11.0 (1.0–22.0)−2.3730.033
MoCA (scores)16.5 (11.0–22.0)17.0 (9.0–20.0)16.0 (12.0–24.0)−1.4590.149
MMSE (scores)26.0 (20.0–28.0)26.0 (21.0–28.0)24.0 (20.0–28.0)0.2540.800

PD: Parkinson’s Disease; M-PD: male patients with PD; F-PD: female patients with PD; TD: tremor-dominant subtype; AR: akinetic-rigid subtype; mixed: mixed subtype; H&Y: Hoehn-Yahr stage; UPDRS -I: United Parkinson’s Disease Ranking Scale Part-I; UPDRS III: United Parkinson’s Disease Ranking Scale part-III; PSQI: Pittsburgh Sleep Quality Index; ESS: Epworth Sleepiness Scale; RBD: Rapid Eye Movement (REM) Sleep Behavior Disorder; RLS: Restless Legs Syndrome; HAMA: Hamilton’s Anxiety Scale; HAMD: Hamilton’s Depression Scale; MMSE: Minimental State Examination; MoCA: Montreal Cognitive Assessment.