Characterizing Advanced Parkinson’s Disease: Romanian Subanalysis from the OBSERVE-PD Study
Table 8
DAT eligibility and fulfillment of each APD indicator.
APD indicator
DAT eligible, n (%)
DAT ineligible, n (%)
Moderate or severe motor fluctuations
46 (65.7)
16 (64)
1
≥2 hours of the waking day with “off” symptoms
43 (61.4)
14 (56)
0.64
Moderate or severe night sleep disturbances
37 (52.9)
14 (56)
0.82
≥2 hours of the day with troublesome dyskinesia
34 (48.6)
6 (24)
0.037
Presence of NMSs fluctuations
56 (80)
18 (72)
0.41
Presence of “off” time at least every 3 hours
33 (47.1)
9 (36)
0.36
≥5 times oral levodopa dosing
27 (38.6)
9 (36)
1
Moderate or severe limitation of ADL capacity
56 (80)
21 (84)
0.77
Falls most of/all of the time
12 (17.1)
2 (8)
0.34
Moderate or severe dementia
8 (11.4)
4 (16)
0.73
Moderate or severe psychosis
4 (5.7)
2 (8)
0.65
ADL: activities of daily living; APD: advanced Parkinson’s disease; DAT: device-aided therapy; and NMSs: nonmotor symptoms. Statistically significant value (0.05) is presented in bold.
