Real-World Experience with Carbidopa-Levodopa Extended-Release Capsules (Rytary^®): Results of a Nationwide Dose Conversion Survey

Table 2

Strategy for determining CD-LD ER dose and frequency (N = 90).

	n (%)
Dosing table (survey question 10)
Not aware	0
Helpful to convert	9 (10)
Not helpful and do not use	34 (38)
Somewhat useful along with own calculations	47 (52)
Dose conversion strategy (survey question 11)
Based on the label	6 (7)
Based on total daily CD-LD IR dose	44 (49)
Based on individual CD-LD IR dose	18 (20)
Other	22 (24)
Dose frequency strategy (survey question 14)
TID and then adjust	20 (22)
QID and then adjust	11 (12)
CD-LD ER dose same as CD-LD IR dose	8 (9)
CD-LD ER dose one less than CD-LD IR dose	24 (27)
CD-LD ER TID or QID if CD-LD IR QID or 5x per day, respectively	27 (30)

CD-LD = carbidopa-levodopa; IR = immediate-release; ER = extended-release; TID = three times a day; QID = four times a day.