Freezing of Gait in Parkinson’s Disease: Risk Factors, Their Interactions, and Associated Nonmotor Symptoms

Table 6

Accuracy of clinical predictors of freezing of gait.

Clinical predictor	Sensitivity (%)	Specificity (%)	Accuracy (%)^1	OR (95% CI)^2
Primary predictors
Bal-Gait score^3 ≥ 4	80	67	72	8.0 (3.8–16.7)
LED^4 ≥ 750 mg	69	71	73	5.4 (2.7–10.7)
Motor Compl. Score^5 ≥ 3	55	80	70	4.8 (2.4–9.7)
MCI or dementia	75	50	60	3.0 (1.5–6.0)
Combined predictors
Bal-Gait score ≥ 4 and LED ≥ 750 mg	84	79	81	20.2 (7.4–54.8)
Bal-Gait score ≥ 4 and motor Compl. score ≥3	87	86	86	40.4 (11.4–143.5)

¹Accuracy, % of subjects correctly classified. ²Relative risk. ³Balance-Gait score = MDS-UPDRS PIGD score minus freezing score. ⁴Levodopa equivalent dose. ⁵MDS-UPDRS motor complications score.