Transcranial Sonography of the Substantia Nigra for the Differential Diagnosis of Parkinson’s Disease and Other Movement Disorders: A Meta-Analysis

Table 2

Subgroup analysis results.

Subgroup		(%)	Pooled sensitivity	Pooled specificity	Pooled diagnostic odds ratio
Age	≥65.0	84.7	0.83 (0.80, 0.86)	0.70 (0.64, 0.75)	24.14 (7.17, 81.63)
	<65.0	53.4	0.88 (0.81, 0.93)	0.75 (0.65, 0.84)	23.28 (7.01, 77.34)
Sample	≥100	88.1	0.82 (0.78, 0.85)	0.68 (0.61, 0.73)	16.39 (4.07, 66.03)
	<100	0.41	0.89 (0.85, 0.93)	0.77 (0.69, 0.83)	26.96 (11.37, 63.96)
Cutoff value	20 mm	71.1	0.91 (0.87, 0.95)	0.79 (0.71, 0.85)	39.63 (11.17, 140.62)
	Not 20 mm	59.2	0.82 (0.78, 0.85)	0.66 (0.60, 0.72)	12.16 (5.28, 27.98)
TCS device	2.5 MHz	0	0.82 (0.78, 0.85)	0.62 (0.55, 0.69)	7.18 (4.96, 10.39)
	Not 2.5 MHz	62.1	0.91 (0.86, 0.95)	0.83 (0.76, 0.88)	43.35 (22.92, 81.96)