Off Time Independently Affects Quality of Life in Advanced Parkinson’s Disease (APD) Patients but Not in Non-APD Patients: Results from the Self-Reported Japanese Quality-of-Life Survey of Parkinson’s Disease (JAQPAD) Study

Table 2

Summary of PDQ-8 domain scores.

	Patients, mean (SD)		value
	Non-APD	APD
Domain
Difficulty getting around	40.7 (32.1)	55.6 (31.4)	<0.0001
Difficulty dressing	39.5 (32.4)	52.8 (30.8)	<0.0001
Felt depressed	28.9 (25.5)	41.7 (27.8)	<0.0001
Problems with close personal relationships	15.8 (22.9)	26.3 (28.5)	<0.0001
Problems with concentration	27.2 (26.7)	39.8 (29.2)	<0.0001
Felt unable to communicate properly	26.3 (27.0)	37.1 (29.9)	<0.0001
Painful muscle cramps or spasm	20.7 (25.3)	32.3 (30.8)	<0.0001
Felt embarrassed in public	17.0 (22.6)	29.0 (28.9)	<0.0001
Summary index	26.9 (18.3)	39.2 (20.5)	<0.0001

APD: advanced Parkinson’s disease; PDQ-8: 8-item Parkinson’s Disease Questionnaire; SD: standard deviation.