Parkinson’s Disease / 2021 / Article / Tab 4 / Research Article
Off Time Independently Affects Quality of Life in Advanced Parkinson’s Disease (APD) Patients but Not in Non-APD Patients: Results from the Self-Reported Japanese Quality-of-Life Survey of Parkinson’s Disease (JAQPAD) Study Table 4 Multiple regression analysis for PDQ-8 SI in patients with non-APD.
Univariate model Multivariate initial model Multivariate final model backward elimination CE 95% CI valueCE 95% CI valueCE Standardized CE 95% CI valueDuration of off time 4.96 2.480, 7.440 <0.0001 0.928 −1.544, 3.400 0.4614 0.352 0.01 −1.973, 2.676 0.7665 Age 0.447 0.277, 0.617 <0.0001 0.152 −0.017, 0.321 0.077 0.159 0.066 −0.004, 0.321 0.0552 Sex (ref: female) 2.608 0.035, 5.180 0.047 0.229 −2.127, 2.585 0.8486 Duration of PD 0.966 0.753, 1.179 <0.0001 0.393 0.175, 0.610 0.0004 0.376 0.12 0.170, 0.582 0.0004 Work status (ref: unemployed) −7.753 −11.846, −3.661 0.0002 −4.849 −8.749, −0.949 0.0149 −4.822 −0.084 −8.616, −1.028 0.0128 Number of PD medication types 1.645 1.073, 2.217 <0.0001 −0.196 −0.790, 0.398 0.5168 NMSQ-TS 1.956 1.751, 2.161 <0.0001 1.863 1.634, 2.091 <0.0001 1.823 0.564 1.608, 2.039 <0.0001 WOQ-9 (ref: absence) 2.934 0.328, 5.540 0.0274 −1.326 −3.883, 1.231 0.309
APD: advanced Parkinson’s disease; CE: coefficient estimate; CI: confidence interval; NMSQ-TS: Nonmotor Symptoms Questionnaire Total Score; PD: Parkinson’s disease; PDQ-8 SI: 8-item Parkinson’s Disease Questionnaire Summary Index; ref: reference; WOQ-9: 9-item Wearing-Off Questionnaire.