Off Time Independently Affects Quality of Life in Advanced Parkinson’s Disease (APD) Patients but Not in Non-APD Patients: Results from the Self-Reported Japanese Quality-of-Life Survey of Parkinson’s Disease (JAQPAD) Study

Table 6

PDQ-8 score assessed for patients meeting (+) or not meeting (−) each 5-2-1 criterion.

Item	n (%)	PDQ-8 SI, mean (SD)
5 (+) 2 (+) 1 (+)	158 (5.5)	44.4 (19.5)
5 (+) 2 (+) 1 (−)	208 (7.3)	37.8 (19.1)
5 (+) 2 (−) 1 (+)	47 (1.6)	36.5 (17.7)
5 (−) 2 (+) 1 (+)	188 (6.6)	43.7 (22.2)
5 (+) 2 (−) 1 (−)	163 (5.7)	33.6 (19.1)
5 (−) 2 (+) 1 (−)	332 (11.6)	35.5 (20.1)
5 (−) 2 (−) 1 (+)	92 (3.2)	39.3 (19.3)
5 (−) 2 (−) 1 (−)	829 (29.1)	26.9 (18.3)

1: troublesome dyskinesia ≥1 hour a day; 2: ≥2 hours of off time a day; 5: ≥5 oral levodopa doses a day; PDQ-8 SI: 8-item Parkinson’s Disease Questionnaire Summary Index; SD: standard deviation.