GuitarPD: A Randomized Pilot Study on the Impact of Nontraditional Guitar Instruction on Functional Movement and Well-Being in Parkinson’s Disease

Table 2

Outcome measurements at the beginning of the trial (week 0) and at pre-intervention baseline (X_b).

Motor and emotion outcomes, mean (SD)	Trial start (week 0)				Preintervention baseline (Xb)
	Group1 (n = 13)	Group 2 (n = 13)	Uncorrected -value	Corrected -value^a	Group1 (n = 13)	Group 2 Week 6 visit (n = 13)	Uncorrected -value	Corrected -value^a
MDS-UPDRS motor total	38.8 (13.6)	36.8 (14.3)	0.71	0.80	38.8 (13.6)	23.8 (13.8)	0.01	0.05
Typing test accuracy, dominant hand	137.0 (78.3)	114.4 (53.2)	0.40	0.53	137.0 (78.3)	111.7 (46.4)	0.33	0.47
Typing test accuracy, non-dominant hand	110.6 (49.2)	106.5 (42.6)	0.82	0.85	110.6 (49.2)	106.6 (42.2)	0.83	0.85
PDQ39 total score	43.2 (20.4)	31.8 (23.0)	0.19	0.32	43.2 (20.4)	30.2 (19.7)	0.11	0.22
Beck depression inventory total score	14.8 (6.3)	10.1 (6.2)	0.07	0.16	14.8 (6.3)	9.9 (7.3)	0.08	0.17
Apathy evaluation scale total score	51.3 (6.6)	55.2 (10.0)	0.26	0.40	51.3 (6.6)	53.7 (11.8)	0.05	0.13
NeuroQoL depression raw score	13.8 (4.2)	11.2 (2.9)	0.08	0.17	13.8 (4.2)	12.5 (6.0)	0.50	0.64
NeuroQoL anxiety raw score	17.2 (5.0)	15.4 (4.4)	0.35	0.50	17.2 (5.0)	15.6 (6.7)	0.52	0.64

^a values are adjusted for multiple comparisons using the Simes method. . .