GuitarPD: A Randomized Pilot Study on the Impact of Nontraditional Guitar Instruction on Functional Movement and Well-Being in Parkinson’s Disease

Table 3

Combined group analysis-effect of intervention immediately after and 6 weeks after completion of the intervention (n = 26).

Outcomes	Changes from preintervention (Xb) to immediately postintervention (Xpi)				Changes from preintervention (Xb) to 6 weeks after completion of intervention
	Coefficient	95% CI	Uncorrected -value	Corrected -value^a	Coefficient	95% CI	Uncorrected -value	Corrected -value^a
MDS-UPDRS motor total	−1.76	−5.4, 1.9	0.34	0.50	−3.80	−7.4, −0.2	0.04	0.12
Typing test accuracy with dominant hand	7.19	−5.6, 20.0	0.27	0.41	11.36	−1.4, 24.1	0.08	0.17
Typing test accuracy with nondominant hand	−0.43	−10.6, 9.8	0.93	0.95	10.16	0.0, 20.3	0.05	0.13
PDQ-39 total score	−5.19	−9.4, −1.0	0.02	0.07	−3.48	−7.7, 0.7	0.10	0.21
Beck depression Inventory-II total score	−3.04	−5.2, −0.9	0.006	0.04	−2.16	−4.3, 0.0	0.05	0.13
Apathy evaluation scale total score	1.74	0.1, 3.4	0.04	0.12	2.36	0.7, 4.0	0.005	0.03
NeuroQoL depression raw score	−1.65	−2.9, −0.4	0.01	0.05	−1.27	−2.5, 0.0	0.049	0.13
NeuroQoL anxiety raw score	−1.83	−3.6, −0.1	0.04	0.12	−0.41	−2.2, 1.4	0.65	0.77

^a values are adjusted for multiple comparisons using the Simes method. . .