Handgrip Strength and Anthropometry in Parkinson’s Disease at Diagnosis
Table 5
Multiple linear regression models, B-value, and value in patients (N = 75) and controls (N = 24) for ECW/ICW ratio, TBW (ECW + ICW, l), FFMI, and FM (%). Interaction between cortisol and phosphate is excluded (not significant).
ECW/ICW ratio
TBW
FFMI
FM (%)
Cases N = 75
Controls N = 24
Cases N = 75
Controls N = 24
Cases N = 75
Controls N = 24
Cases N = 75
Controls N = 24
Age, years
0.007 (<0.001)
0.007 (0.054)
−0.141 (0.033)
−0.382 (<0.001)
−0.006 (0.823)
−0.036 (0.303)
0.135 (0.041)
0.146 (0.317)
BMI (kg/m2)
−0.004 (0.327)
−0.002 (0.577)
0.515 (<0.001)
0.880 (<0.001)
0.324 (<0.001)
0.413 (<0.001)
0.615 (<0.001)
0.705 (0.002)
Sex, M = 0 F = 1
0.055 (0.121)
0.022 (0.627)
−9.175 (<0.001)
−9.515 (<0.001)
−1.961 (<0.001)
−1.621 (0.003)
7.961 (<0.001)
6.169 (0.006)
P-cortisol (μmol/l)
0.000 (0.662)
0.000 (0.239)
−0.010 (0.019)
0.000 (0.978)
−0.003 (0.040)
−0.001 (0.675)
0.007 (0.090)
0.006 (0.479)
P-phosphate (mmol/l)
−0.052 (0.652)
−0.124 (0.469)
1.159 (0.759)
6.051 (0.162)
−0.522 (0.727)
0.346 (0.847)
−1.362 (0.713)
−1.852 (0.806)
UPDRS-III
0.005 (0.006)
—
−0.154 (0.007)
—
−0.047 (0.034)
—
0.052 (0.348)
—
R2
0.379
0.318
0.641
0.942
0.558
0.887
0.562
0.613
UPDRS = Unified Parkinson’s Disease Rating Scale. BMI = body mass index (kg/m2). ECW = Extracellular Water, l. ICW = intracellular water, l. TBW = total body water (ECW + ICW). FFMI = fat-free mass index (kg/m2). FM (%) = fat mass percent. The significance level is 95% CI ∗p<0.05.