Gastrointestinal Dysfunction Impact on Life Quality in a Cohort of Russian Patients with Parkinson’s Disease I-III H&Y Stage
Таble 1
Demographic and baseline clinical characteristics of the patients.
Data
Mean (%)
SD
Range
Age (years)
63.33
8.265
42–80
PD duration (years)
4.65
2.58
1–13
Levodopa (mg)
215.41
254.474
0–1000
Stage H&Y (1–5)
2.5 (2, 3)
—
1–3
UPDRS-III (on state) (0–56)
28.51
10.7
8–64
PDQ-39SI (total score 0–156)
28.96 (45.17)
16.48 (25.723)
2.56–83.97 (4–131)
PDQ-39 mobility (0–40 score)
29.90 (11.94)
22.48 (8.993)
0–95 (0–38)
PDQ-39 daily activity (0–24 score)
31.3 (7.45)
23.80 (5.713)
0–100 (0–24)
PDQ-39 emotional wellbeing (0–24 score)
32.01 (7.72)
21.37 (5.129)
0–100 (0–24)
PDQ-39 stigma (0–16 score)
37.10 (5.99)
27.45 (4.393)
0–100 (0–16)
PDQ-39 social support (0–12 score)
15.76 (1.90)
19.60 (2.352)
0–75 (0–9)
PDQ-39 cognition (0–16 score)
26.35 (4.20)
19.09 (3.055)
0–100 (0–16)
PDQ-39 communication (0–12 score)
18.16 (2.17)
20.26 (2.432)
0–83.33 (0–10)
PDQ-39 bodily discomfort (0–12 score)
31.68 (3.82)
22.77 (2.733)
0–83.33 (0–10)
GSRS-SI (total score 0–90)
12.27 (11.05)
11.43 (10.287)
0–48.89 (0–44)
GSRS abdominal pain (0–12 score)
10.43 (1.25)
14.20 (1.704)
0–66.67 (0–8)
GSRS reflux (0–18 score)
8.13 (1.46)
10.62 (1.913)
0–38.89 (0–7)
GSRS diarrhea (0–18 score)
4.32 (0.78)
10.24 (1.844)
0–66.67 (0–12)
GSRS indigestion (0–24 score)
14.98 (3.60)
19.06 (4.576)
0–83.33 (0–20)
GSRS constipation (0–18 score)
21.94 (3.95)
23.94 (4.310)
0–100 (0–18)
GDSS (0–20 score)
3.37
3.625
0–19
MMSE (0–30 score)
28.29
1.562
24–30
BDI (0–63 score)
11.81
7.470
0–33
STAI-S
44.18
11.548
20–75
STAI-T
48.35
10.101
20–90
SD: standard deviation; H&Y: Hoehn and Yahr Rating Scale; UPDRS-III: The Unified Parkinson’s Disease Rating Scale part III; PDQ-39: the Parkinson’s Disease Questionnaire; SI: summary index; GSRS: gastrointestinal symptom rating scale; GDSS: Glasgow Dyspepsia Severity Score; MMSE: Mini Mental State Examination; BDI: Beck Depression Inventory; STAI-S: state subscale of the State-Trait Anxiety Inventory; STAI-T: trait subscale of the State-Trait Anxiety Inventory. Me (Q1; Q3).
