Two-Channel Portable Biopotential Recording System Can Detect REM Sleep Behavioral Disorder: Validation Study with a Comparison of Polysomnography
Table 1
Basic characteristics of subjects with Parkinson’s disease.
Patient 1
Patient 2
Patient 3
Patient 4
Patient 5
Patient 6
Patient 7
Patient 8
Age/gender
67/M
57/M
66/F
70/F
61/M
50/M
78/M
76/F
Disease duration (years)
5
11
11
12
11
10
10
17
Hypertension
−
−
−
+
−
−
−
−
Body mass index
20.5
19.4
20.2
22.6
27.2
19.4
21.7
16.1
Hoehn–Yahr stage
2
2
2
4
4
4
4
5
MDS-UPDRS part 3
32
10
7
38
22
25
28
57
MDS-UPDRS part 4
5
11
4
7
7
7
4
7
MoCA-J
25
23
26
22
25
29
26
23
Psychosis
0
2
2
11
4
0
3
0
Anxiety
2
12
0
3
17
6
6
2
Levodopa (mg/day)
50
700
600
400
550
LCIG
1100
400
Dopamine agonists (DA)
+
+
+
+
+
−
+
+
Long-acting DA
+
+
+
+
+
−
+
+
Sleeping drug
−
+
−
+
+
−
−
+
PDSS-2 total score
17
32
21
21
20
27
43
36
Disturbed sleep on PDSS-2
10
15
14
13
9
14
15
10
Motor symptoms at night on PDSS-2
4
9
4
2
5
8
15
11
PD symptoms at night on PDSS-2
3
7
3
6
6
5
13
14
PSQI total score
6
14
13
15
14
10
15
10
Beck depression score
14
28
16
21
23
20
27
20
RBD score
9
7
2
9
2
4
12
6
MDS-UPDRS: Movement Disorder Society Revision of the Unified PD Rating Scale; LCIG: continuous intrajejunal infusion of levodopa-carbidopa intestinal; MoCA-J: Japanese version of the Montreal Cognitive Assessment; PDSS: PD Sleep Scale; PSQI: Pittsburgh Sleep Questionnaire Index; RBD: REM sleep behavior disorder. MDS-Non-Motor Rating Scale.