Research Article
MAO-B Polymorphism Associated with Progression in a Chinese Parkinson’s Disease Cohort but Not in the PPMI Cohort
Table 3
Association between SNPs and PCA progression in the TW and PPMI cohorts.
| Cohort | Gene | SNP | PC | Estimate (95% CI) | value | Type |
| PPMI | SYT4.RIT2 | rs12456492 | PC1 | −0.333 (−0.536–0.131) | 0.0013333 | Motor PCA | TW | MAO-B | rs1799836 | PC2 | 0.402 (0.219–0.586) | 0.0000686 | Nonmotor PCA | MAO-B | rs1799836 | PC3 | 1.584 (0.957–2.21) | 0.0000084 | MAO-B | rs1799836 | PC1 | 0.457 (0.247–0.666) | 0.0000765 | TW | MAO-B | rs1799836 | PC1 | -−839 (−1.336–0.342) | 0.0014921 | Composite PCA |
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PC, principal component; PCA, principal component analysis.
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