Research Article

MAO-B Polymorphism Associated with Progression in a Chinese Parkinson’s Disease Cohort but Not in the PPMI Cohort

Table 5

Summary of polymorphisms correlated with PD progression among diverse populations.

Correlation settingCohortPolymorphism

Mild settingPPMI CaucasiansSYT4.RIT2, PTHLH, PRKN, MAPT, LOC105377329, SNCA haplotype, PARK16 haplotype, CCDC62
All AsianSYT4.RIT2, RAB29, PRKN, PLA2G6, NUCKS1, MAO-B, LRRK2 haplotype, LRRK2, HLA-DRA, COMT, SNCA haplotype, PARK16 haplotype
PPMI AsianSYT4.RIT2, RAB29, PLA2G6, PARK7, MAPT, MAO-B, LRRK2 haplotype, LRRK2, LOC105377329, GPNMB, COMT, BST1
TWSYT4.RIT2, PRKN, PLA2G6, MAO-B, LRRK2 haplotype, LRRK2 R1628P.H, LRRK2 G2385 R, COMT
Strict settingPPMI CaucasiansSYT4.RIT2, SNCA haplotype
All AsianPRKN, NUCKS1, MAO-B, SNCA haplotype, PARK16 haplotype
TWMAO-B