Nomogram for Prediction of Postoperative Delirium after Deep Brain Stimulation of Subthalamic Nucleus in Parkinson’s Disease under General Anesthesia

Table 2

Univariate and multivariate analyses of postoperative delirium in PD patients after STN-DBS under general anesthesia.

	Univariate analysis				Multivariate analysis
	Odds ratio	Lower	Upper		Odds ratio	Lower	Upper
Smoker (current/former)	2.73	1.10	6.79	0.03	4.51	1.56	13.02	<0.01
Cardiac disease	3.19	1.07	9.48	0.04
History of drug-induced hallucination	2.48	1.09	5.62	0.03
HAMA score	1.87	1.19	2.95	<0.01	2.12	1.28	3.50	<0.01
Orthostatic hypotension	4.33	1.36	13.81	0.01	3.42	0.90	13.06	0.07
Plasma APOE level (mg/L)				0.04	1.48	0.95	2.29	0.08
Low (<27)	0.46	0.21	1.02	0.06
High (>45)	1.86	0.50	6.96	0.36
Silent brain infarction/ischemia	2.55	1.08	6.23	0.03	2.36	0.90	6.14	0.08
MAOBIs	2.98	1.29	6.87	0.01	3.07	1.17	8.04	0.02
Use of etomidate	2.79	1.22	6.40	0.02
Use of dexamethasone	0.34	0.16	0.73	0.01

Significance was recognized when . PD, Parkinson’s disease; STN, subthalamic nucleus; DBS, deep brain stimulation; HAMA, Hamilton anxiety scale; APOE, apolipoprotein E; MAOBIs, type-B monoamine oxidase inhibitors.