Research Article
Nomogram for Prediction of Postoperative Delirium after Deep Brain Stimulation of Subthalamic Nucleus in Parkinson’s Disease under General Anesthesia
Table 2
Univariate and multivariate analyses of postoperative delirium in PD patients after STN-DBS under general anesthesia.
| | Univariate analysis | Multivariate analysis | Odds ratio | Lower | Upper | | Odds ratio | Lower | Upper | |
| Smoker (current/former) | 2.73 | 1.10 | 6.79 | 0.03 | 4.51 | 1.56 | 13.02 | <0.01 | Cardiac disease | 3.19 | 1.07 | 9.48 | 0.04 | | | | | History of drug-induced hallucination | 2.48 | 1.09 | 5.62 | 0.03 | | | | | HAMA score | 1.87 | 1.19 | 2.95 | <0.01 | 2.12 | 1.28 | 3.50 | <0.01 | Orthostatic hypotension | 4.33 | 1.36 | 13.81 | 0.01 | 3.42 | 0.90 | 13.06 | 0.07 | Plasma APOE level (mg/L) | | | | 0.04 | 1.48 | 0.95 | 2.29 | 0.08 | Low (<27) | 0.46 | 0.21 | 1.02 | 0.06 | | | | | High (>45) | 1.86 | 0.50 | 6.96 | 0.36 | | | | | Silent brain infarction/ischemia | 2.55 | 1.08 | 6.23 | 0.03 | 2.36 | 0.90 | 6.14 | 0.08 | MAOBIs | 2.98 | 1.29 | 6.87 | 0.01 | 3.07 | 1.17 | 8.04 | 0.02 | Use of etomidate | 2.79 | 1.22 | 6.40 | 0.02 | | | | | Use of dexamethasone | 0.34 | 0.16 | 0.73 | 0.01 | | | | |
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Significance was recognized when . PD, Parkinson’s disease; STN, subthalamic nucleus; DBS, deep brain stimulation; HAMA, Hamilton anxiety scale; APOE, apolipoprotein E; MAOBIs, type-B monoamine oxidase inhibitors. |