The Origin of Abnormal Beta Oscillations in the Parkinsonian Corticobasal Ganglia Circuits

Figure 1

Schematic illustration of the CBGTC loop. The classical model of the BG consists of the opposing direct and indirect pathways. The hyperdirect and DAergic pathways are also shown. (a) CBGTC loop in the normal state. (b) CBGTC loop in the PD state characterized by loss of DA and alteration of inputs. Green and red arrows represent excitatory and inhibitory inputs, respectively. Thickness of arrows indicates the strength of inputs.

(a)

(b)