Parkinson’s Disease / 2022 / Article / Tab 1 / Review Article
The Origin of Abnormal Beta Oscillations in the Parkinsonian Corticobasal Ganglia Circuits Table 1 Changes of the neuronal mean firing rates within the cortico-BG circuits observed in 6-OHDA rats/mice or MPTP monkeys in control (normal) and parkinsonian condition.
Mean firing rate ± SD (Hz) No. Nuclei Control PD Animal model Reference 1 Cortex 5.0 ± 0.8 4.5 ± 0.5 MPTP monkey Goldberg et al. [27 ] 2 D1 MSN 1.61 ± 0.19 0.11 ± 0.04 6-OHDA mouse Ryan et al. [29 ] 3 D2 MSN 1.42 ± 0.28 1.24 ± 0.23 6-OHDA mouse Ryan et al. [29 ] 2.1 ± 1.2 6.4 ± 2.7 6-OHDA rat Kita and Kita [12 ] 4 GPe 33.7 ± 1.3 14.6 ± 0.4 6-OHDA rat Mallet et al. [8 ] 29.3 ± 12.2 26.2 ± 10.2 6-OHDA rat Kita and Kita [12 ] 24.5 ± 1.14 18.9 ± 0.87 6-OHDA mouse Corbit et al. [30 ] 76.0 ± 28.0 51.0 ± 27.0 MPTP monkey Filion and Tremblay [31 ] 5 STN 18.8 ± 10.3 25.8 ± 14.9 MPTP monkey Bergman et al. [32 ] 13.8 ± 2.7 34.0 ± 3.4 6-OHDA rat Mallet et al. [10 ] 11.8 ± 0.7 17.1 ± 1.0 6-OHDA rat Breit et al. [16 ] 6 SNr 15.2 ± 6.1 21.3 ± 7.4 6-OHDA rat Benazzouz et al. [33 ] 7 GPi 28.0 ± 9.1 29.3 ± 11.3 6-OHDA rat Kita and Kita [34 ] 57.3 ± 17.3 77.9 ± 26.4 MPTP monkey Leblois et al. [35 ]