Short-Term Motor Outcomes in Parkinson’s Disease after Subthalamic Nucleus Deep Brain Stimulation Combined with Post-Operative Rehabilitation: A Pre-Post Comparison Study
Table 1
Demographic data of the participants.
Total (n = 60)
PI ≥ 3 (n = 18)
PI < 3 (n = 42)
value between PI ≥ 3, PI < 3
Age, years
60.7 (8.9)
61.2 (9.9)
60.5 (8.6)
0.81
Sex, female/male
28 (47%)/32 (53%)
13 (72%)/5 (28%)
15 (36%)/27 (64%)
—
Duration of disease, years
12.2 (4.6)
12.8 (4.3)
11.9 (4.8)
0.49
Duration of medication, years
10.6 (4.1)
10.1 (4.1)
11.9 (4.0)
0.12
H & Y stage (on-state)
2.4 (0.7)
2.8 (0.5)
2.2 (0.7)
<0.001
MDS-UPDRS part III score of preoperation (on-state)
18.1 (8.6)
24.9 (6.9)
15.1 (7.6)
<0.001
MDS-UPDRS part III 12 postural stability score of preoperation (on-state)
1.2 (1.3)
3.0 (0)
0.4 (0.6)
<0.001
Final stimulation setting
Pulse, microseconds
58.8 (4.9)
57.2 (7.3)
59.4 (3.3)
0.24
Hz
131.2 (6.5)
131.0 (7.1)
131.2 (6.3)
0.90
mA
1.8 (0.5)
1.8 (0.5)
1.8 (0.5)
0.97
Preoperative LDD
740 (272)
806 (275)
712 (269)
0.22
Discharge LDD
332 (218)
300 (227)
345 (216)
0.46
Preoperative LEDD
1464 (490)
1549 (456)
1439 (496)
0.43
Discharge LEDD
847 (456)
846 (502)
844 (444)
0.99
Duration of hospitalization, days
25.2 (16.9)
24.7 (14.3)
25.4 (18.1)
0.88
Data are means (SD), n (%). abbreviations: H & Y, Hoehn and Yahr; MDS-UPDRS, movement disorders society-unified Parkinson’s disease rating scale; PI, MDS-UPDRS part III 12 postural instability score; LDD, levodopa daily dose; LEDD, levodopa equivalent daily dose.
