DRD2 Taq1A Polymorphism-Related Brain Volume Changes in Parkinson’s Disease: Voxel-Based Morphometry

Table 2

Demographic and clinical characteristics of PD patients.

	A1 carrier	A2 homo carrier	value
Number, n (%)	77 (74.8)	26 (25.2)
Female, n (%)	31 (40.3)	11 (42.3)	1
Age, mean ± SD	67.43 ± 11.23	70.00 ± 7.87	0.283
Disease duration, mean ± SD	7.77 ± 5.40	5.73 ± 3.35	0.074
TBV, mean ± SD, ml	1049.41 ± 129.57	1043.51 ± 121.92	0.839
Dyskinesia, n (%)	28 (36.4)	4 (15.4)	0.08
UPDRS, mean ± SD	25.71 ± 16.18	21.96 ± 11.76	0.283
MMSE, mean ± SD	27.73 ± 2.89	27.17 ± 3.13	0.48
Total LED, mean ± SD, mg/day	636.45 ± 372.69	525.57 ± 402.48	0.206

TBV, total brain volume; UPDRS, Unified Parkinson’s Disease Rating Scale; MMSE, Mini-Mental State Examination scores; LED, levodopa-equivalent dose.