Research Article

Genome- and Exome-Wide Association Studies Revealed Candidate Genes Associated with DaTscan Imaging Features

Table 3

Top eQTLs in one of three PD-related tissues (substantia nigra, caudate nucleus, and putamen nucleus) with their positional and functional mapped genes.

ChrSNP/indelMapped geneTop gene with significant eQTL value

1exm1952
rs78555129
C1QTNF12ANKRD65 and B3GALT6

1exm1971
rs12093154
C1QTNF12ANKRD65 and B3GALT6

1exm156096
rs1188732
OBSCNOBSCN and WNT3A

1exm2250840
rs12035900
OBSCNOBSCN and WNT3A

4NeuroX_rs3736087GAKIDUA

4NeuroX_rs3775119GAKIDUA

6exm563164
rs4706980
DOP1AUBE3D

8exm692355
rs3779620
PBKCCDC25

8exm692255
rs4732748
ESCO2CCDC25

8rs2280838SLC39A4VPS28

9rs15394CTSVGAS21LP2

9rs62560873GAS21LP2GAS21LP2

9rs16924211GAS21LP2GAS21LP2

19exm1511712
rs3752176
ZNF471ZNF471 and AC007228.11

19exm1511688
rs11667052
ZNF471ZNF471 and AC007228.11

19exm1426190
rs3087689
KRI1KRI1