Clinical Study

The Frequency of Epidermal Growth Factor Receptor Mutation of Nonsmall Cell Lung Cancer according to the Underlying Pulmonary Diseases

Table 3

Characteristics of patients with an EGFR mutation treated with gefitinib.

Total number43

Age (median, range)67, 28–92
Gender
 Male13
 Female30
Smoking-status
 Never24
 Ex/Current19
 Pack-years of smokers (median, range)33, 2.5–225
Histology
 Adenocarcinoma42
 Squamous cell carcinoma1
Clinical stage of NSCLC
 IB2
 IIIA1
 IIIB7
 IV22
 Recurrence11
History of chemotherapy before gefitinib treatment
 No28
 Yes15
EGFR mutation
 Ex18 G719C1
 Ex19 del30
 Ex21 L858R10
 Ex19 del + Ex21L858R1
 Ex19 del + Ex20 T790M1
Chest CT
 Normal36
 Emphysema6
 Fibrosis1