Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD

Table 1

General characteristics of the study subjects stratified for gender.

	Subjects without COPD		Subjects with COPD
	Men	Women	Men	Women
No. of subjects, n	238	221	299	164
Age, y	55.9 ± 9.6	54.8 ± 9.1	65.2±9.4^∗	62.6±9.0^∗,†
FEV1, %pred	93.9 ± 8.4	95.9 ± 9.4^†	52.6±17.4^∗	53.1±16.1^∗
FEV1/FVC	0.79 ± 0.04	0.79 ± 0.04	0.52±0.13^∗	0.54±0.12^∗,†
Weight, kg	86.0 ± 13.1	70.9 ± 12.8^†	79.5±14.9^∗	66.3±16.0^∗,†
BMI, kg/m^2	27.0 ± 3.4	25.8 ± 4.5^†	25.8±4.2^∗	24.9 ± 5.6
FFMI, kg/m^2	19.3 ± 1.6	16.8 ± 1.7^†	18.7±1.6^∗	15.8±1.9^∗,†
FMI, kg/m^2	7.7 ± 2.6	8.9 ± 3.5^†	7.1±2.8^∗	9.1±3.9^†
Lung mass, g	905.2 ± 138.9	753.0 ±113.5^†	875.0±134.5^∗	716.9±109.2^∗,†
No. of pack years, y	21.2 ± 14.4	17.2 ± 12.6^†	33.9±18.6^∗	25.5±14.2^∗,†
AWT-Pi10, cm	0.49 ± 0.03	0.46 ± 0.03^†	0.50±0.03^∗	0.47±0.03^∗,†
%LAA^(logtransformed)	1.04 ± 1.05	0.72 ± 0.89	12.43±11.78^∗	9.94±11.66^∗,†

Data are mean ±SD. FEV1: forced expiratory volume in one second, FEV1/FVC: tiffeneau index, BMI: body mass index, FFMI: fat-free mass index, FMI: fat mass index, AWT-Pi10: standardized airway wall thickness at an internal perimeter of 10 mm, %LAA: percentage low attenuation areas less than −950 HU. ^∗𝑃<.05versus subjects without COPD, ^†𝑃<.05versus male counterparts.