Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD

Table 3

Multiple linear regression analyses of change in emphysema level (%LAA) and change in airway wall thickness (AWT-Pi10) by level fat-free mass index (FFMI) and level of fat mass index (FMI).

	Log(%LAA)^∗			AWT-Pi10^∗∗
	Beta	SE	P value	Beta	SE	P-value
Subjects without COPD
FFMI	−0.04	0.02	.528	0.16	0.01	.002
FMI	0.09	0.01	.053	0.22	0.01	<.001
Adjusted R^2	0.26			0.33
Subjects with COPD
FFMI	−0.28	0.02	.002	0.08	0.02	.460
FMI	0.03	0.01	.686	0.20	0.01	.020
Adjusted R^2	0.48			0.30

%LAA: percentage low attenuation areas less than −950 HU, AWT-Pi10: standardized airway wall thickness at an internal perimeter of 10 mm, FFMI: fat-free mass index, FMI: fat mass index.
^∗Adjusted for age, pack year, FEV1 (%pred), and AWT-Pi10,
^∗∗Adjusted for age, pack year, FEV1 (%pred), and %LAA.