Review Article

Diffuse Alveolar Damage: A Common Phenomenon in Progressive Interstitial Lung Disorders

Table 4

Associations of DAD with interstitial lung diseases and severe lung reactions (reference number in parentheses).

AIP[28]
AE of IPF[33, 35, 44]
AE of NSIP[39]
AE of CVD associated UIP and NSIP[39]
AE of allergic alveolitis[52]
ARDS[75, 76]
 - Infections
 - Organ or stem cell transplantation
 - Drug reaction
 - Radiation therapy
Viral lung infections[79]
 - SARS[80, 81]
 - H1N1-influenza A[83]

AE: acute exacerbation
UIP: usual interstitial pneumonia
IPF: idiopathic pulmonary fibrosis
NSIP: nonspecific interstitial pneumonia
CVD: collagen vascular disease.