A Normal Range of KL-6/MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography

Table 1

Characteristics of asymptomatic and symptomatic patients with honeycombing on HRCT.

	Asymptomatic	Symptomatic	P values
Patients (M/F)	10/1	15/2
Age yrs	67 ± 3 (𝑛=11)	66 ± 2 (𝑛=17)	.32
Smoking Current/Ex/Never	5/2/1	5/4/5	.44
Pack-yrs	33.3 ± 6.3 (𝑛=8)	33.1 ± 7.6 (𝑛=14)	.60
VC %pred	96.9 ± 6.1 (𝑛=9)	88.1 ± 3.6 (𝑛=15)	.25
FEV1.0/FVC (%)	82.3 ± 3.4 (𝑛=9)	84 ± 2.2 (𝑛=15)	.61
DLCO  %pred	79.3 ± 6.1 (𝑛=6)	58.3 ± 5.8 (𝑛=14)	.031*
RV/TLC %	32.6 ± 1.8 (𝑛=5)	34.5 ± 2.0 (𝑛=15)	.36

Data are presented as mean ± S.E. VC: vital capacity. EFV_1.0: forced expiratory volume in one second. FEV: forced expiratory volume. DL_CO: diffusing capacity of lung for carbon monoxide. RV/TLC: Residual volume/Total lung capacity. *: <.05.