Clinical Study

Patient Characteristics in Persistent Pulmonary Hypertension of the Newborn

Table 3

Patient characteristics of surviving patients.

Gestational Age (GA)<37 weeks≥37 weeksP-value

Total2765
Female629.04
Inhaled NO1844
Severity PPHN
 Severe1731
 Severe (iNO)1121
 Mild-moderate1034
 Mild-moderate (iNO)723
Severity (OI)
 Mild <1513
 Moderate 15–2517
 Severe 25–4018
 Very severe >40 14
Pathophysiology
 Maldevelop/maladap2260
 Maldevelop/maladap + iNO1542
 Underdevelopment55
 Underdevelopment + iNO32
Comorbidity (n/%)
 CHD (TGA)114.03
 Asphyxia210
 Lunghypoplasia nos40.001
 Lunghypoplasia (neuromuscular)00
 Lunghypoplasia (omphalocele)00
 Lunghypoplasia/CDH05
 Lunghypoplasia/cystic kidneys10
 Infection511
 Emphysema10
 Hydrops fetalis (unknown origin)00

OI = oxygen index, Maldevelop/maladap = maladevelopment/maladptation, CHD = congenital heart disease.