Clinical Study
Patient Characteristics in Persistent Pulmonary Hypertension of the Newborn
Table 3
Patient characteristics of surviving patients.
| Gestational Age (GA) | <37 weeks | ≥37 weeks | P-value |
| Total | 27 | 65 | | Female | 6 | 29 | .04 | Inhaled NO | 18 | 44 | | Severity PPHN | | | | Severe | 17 | 31 | | Severe (iNO) | 11 | 21 | | Mild-moderate | 10 | 34 | | Mild-moderate (iNO) | 7 | 23 | | Severity (OI) | | | | Mild <15 | | 13 | | Moderate 15–25 | | 17 | | Severe 25–40 | | 18 | | Very severe >40 | | 14 | | Pathophysiology | | | | Maldevelop/maladap | 22 | 60 | | Maldevelop/maladap + iNO | 15 | 42 | | Underdevelopment | 5 | 5 | | Underdevelopment + iNO | 3 | 2 | | Comorbidity (n/%) | | | | CHD (TGA) | 1 | 14 | .03 | Asphyxia | 2 | 10 | | Lunghypoplasia nos | 4 | 0 | .001 | Lunghypoplasia (neuromuscular) | 0 | 0 | | Lunghypoplasia (omphalocele) | 0 | 0 | | Lunghypoplasia/CDH | 0 | 5 | | Lunghypoplasia/cystic kidneys | 1 | 0 | | Infection | 5 | 11 | | Emphysema | 1 | 0 | | Hydrops fetalis (unknown origin) | 0 | 0 | |
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OI = oxygen index, Maldevelop/maladap = maladevelopment/maladptation, CHD = congenital heart disease.
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