Gradual Increase of High Mobility Group Protein B1 in the Lungs after the Onset of Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Figure 3
Quantitative distribution of HMGB1-positive cells in lung tissues. (a) The distribution patterns of the cells positive for HMGB1 were quantified in the autopsied lung tissues after acute exacerbation in 8 IPF patients (AEx IPF), using the biopsied lung tissues of 10 patients with stable IPF and three controls. (b) The percentages of immunoreactive cells with nuclear or cytoplasmic staining for HMGB1 are shown. The cells with both cytoplasmic and nuclear staining for HMGB1 were counted as cytoplasmic.
