Clinical Study

Significant Differences in Markers of Oxidant Injury between Idiopathic and Bronchopulmonary-Dysplasia-Associated Pulmonary Hypertension in Children

Table 3

Hemodynamics of subjects in catheterization laboratory.

IPHPH due to BPDASD controlsP value
IPH versus BPD

N4125
RVP/LVP (%)83 (80–1.1)46 (38–59).24 (.22–.25).08*
Pulmonary vascular resistance (WUs)17.2 (16.2–19.6)4 (3.5–5.4)1.4 (1.1–1.6).08*
Mean PAP†† (mmHg)61 (53–63)25 (22–36)17 (14–19).08*
RVEDP (mmHg)10 (8–10)7.5 (6.3–9)8 (7.5–8.5).26*
LVEDP6 (mmHg)8 (8–9)8 (7–9)10 (8–10).99*
Cardiac index (L/min/m2)3.6 (3.1–3.6)3.6 (3.5–3.8)3.0 (2.7–3.5).99*
Qp : Qs§.87 (0.8-.94)1.0 (1.0-1.0)2.1 (1.6–4.1).53*
Baseline FiO2(%)21 (21–26)21 (21-22)21 (21–21).52*
ASD (# patients)275.62**

*Value based on Mann-Whitney U test.
**Value based on Fisher’s exact test.
Indexed to body surface area.
††Pulmonary artery pressure.
Right ventricular end diastolic pressure.
‡‡Left ventricular end diastolic pressure.
§Ratio of pulmonary to systemic blood flow.
Interval data expressed as median (IQR).