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Pulmonary Medicine
Volume 2012, Article ID 542769, 6 pages
http://dx.doi.org/10.1155/2012/542769
Review Article

Lung Compliance and Chronic Obstructive Pulmonary Disease

4th Department of Pulmonology, Athens Hospital for Chest Diseases “Sotiria”, 152 Mesogeion Street, Athens 11527, Greece

Received 7 September 2012; Accepted 21 September 2012

Academic Editor: Kostas Spiropoulos

Copyright © 2012 D. Papandrinopoulou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Chronic obstructive pulmonary disease, namely, pulmonary emphysema and chronic bronchitis, is a chronic inflammatory response of the airways to noxious particles or gases, with resulting pathological and pathophysiological changes in the lung. The main pathophysiological aspects of the disease are airflow obstruction and hyperinflation. The mechanical properties of the respiratory system and its component parts are studied by determining the corresponding volume-pressure (P-V) relationships. The consequences of the inflammatory response on the lung structure and function are depicted on the volume-pressure relationships.