Research Article
Successful Smoking Cessation in COPD: Association with Comorbidities and Mortality
Table 1
Demographics and clinical characteristics of quitters and nonquitters.
| Characteristics | All | Quitters1 | Nonquitters | P value | N = 739 (%) | N = 433 (%) | N = 306 (%) |
| Men | 473 (64) | 285 (60.3) | 188 (39.7) | NS | Women | 266 (36) | 148 (55.6) | 118 (44.4) |
Age, mean (SD) in years | 64.0 (6.8) | 65.3 (6.6) | 62.3 (6.8) | <0.001 | Duration of COPD mean (SD) in years | 5.5 (4.1) | 5.8 (4.4) | 5.2 (3.8) | NS | BMI (kg/m2) (SD) | 26.5 (5.3) | 26.5 (5.2) | 26.5 (5.5) | NS | Pack years (SD) | 41 (23) | 43 (24) | 38 (22) | 0.01 | Baseline mean (SD) | | | | | FEV1 % predicted | 58.4 (18.9) | 56.3 (18.4) | 61.3 (19.3) | <0.001 | FVC % predicted | 73.6 (18.1) | 72.6 (17.9) | 74.9 (18.3) | 0.04 | FEV1/FVC % | 64.0 (13.9) | 62.7 (14.4) | 65.8 (13.0) | 0.002 | After bronchodilatation mean (SD) | | | | | FEV1 % predicted | 62.1 (18.3) | 60.3 (18.1) | 64.4 (18.4) | 0.004 | FVC % predicted | 77.8 (17.3) | 77.4 (17.2) | 78.4 (17.3) | NS | FEV1/FVC % | 64.4 (13.9) | 63.0 (14.4) | 66.4 (13.0) | 0.002 | (%) of patients with | | | | | FEV1 % >80 | 87 (12.0) | 41 (9.6) | 46 (15.4) | 0.005 for trend | FEV1 % 65–80 | 191 (26.4) | 100 (23.5) | 91 (30.5) | FEV1 % 40–64 | 309 (42.7) | 196 (46.1) | 113 (37.9) | FEV1% <40 | 139 (18.8) | 88 (20.7) | 48 (16.1) | General-health-related QoL score (range 0-1) (SD) | 0.79 (0.11) | 0.80 (0.10) | 0.78 (0.12) | 0.05 | Airway specific QoL score (range 20–0) (SD) | 8.25 (5.03) | 7.98 (4.77) | 8.63 (5.35) | NS | Comorbidities N (%) | | | | | Cardiovascular diseases | 216 (29.2) | 141 (32.6) | 75 (24.5) | 0.02 | Diabetes | 121 (16.4) | 72 (16.7) | 49 (16.1) | NS | Alcohol abuse | 129 (17.8) | 49 (11.5) | 80 (26.6) | <0.001 | Psychiatric disorder | 177 (24.1) | 75 (17.5) | 102 (33.6) | <0.001 | Cancer | 78 (10.6) | 49 (11.3) | 29 (9.5) | NS | Deceased during the followup | 114 (15.3) | 52 (12.2) | 62 (20.7) | 0.002 |
|
|
1Early and late quitters combined.
|