Successful Smoking Cessation in COPD: Association with Comorbidities and Mortality

Table 3

Underlining clinical characteristics that predict mortality of the COPD patients during the four-year followup.

Variables	Patient N = 739	Deceased %	Crude OR	95% CI	P value	Adjusted; OR	95% CI	P value
Aging by one year			1.05	1.02–1.09	0.002	1.07	1.03–1.11	0.001
Gender
Male	466	18.0	1.00			1.00
Female	259	11.6	0.60	0.38–0.93	0.022	0.81	0.48–1.435	NS
Smoking cessation
Yes	426	12.2	1.00			1.00
No	299	20.7	1.88	1.26–2.82	0.002	2.50	1.55–4.03	<0.001
Cardiovascular diseases
No	514	13.0	1.00			1.00
Yes	211	22.3	1.91	1.26–2.89	0.002	1.52	0.94–2.46	NS
Diabetes
No	606	14.5	1.00			1.00
Yes	117	22.8	1.68	1.03–2.75	0.036	1.38	0.79–2.43	NS
Alcohol abuse
No	584	13.7	1.00			1.00
Yes	128	24.2	2.01	1.26–3.22	0.003	2.03	1.14–3.61	0.016
Psychiatric condition
No	544	14.9	1.00			1.00
Yes	175	17.1	1.18	0.75–1.87	NS	1.32	0.77–2.26	NS
Cancer
No	649	13.7	1.00			1.00
Yes	74	32.4	3.02	1.77–5.16	<0.001	3.08	1.70–5.59	<0.001
FEV1 % of predicted
>80%	87	5.7	1.00			1.00
80–65%	191	9.9	1.81	0.65–5.02	NS	2.12	0.68–6.67	NS
65–40%	306	16.5	3.24	1.25–8.40	0.015	3.76	1.27–11.15	0.017
<40%	136	28.7	6.59	2.48–17.51	<0.001	8.77	2.88–26.68	<0.001

Response (dead = 1, alive = 0).