Levels of Interferon-Gamma Increase after Treatment for Latent Tuberculosis Infection in a High-Transmission Setting
IFN-γ levels before and after H treatment for LTBI measured by QFT-IT stratified by baseline QFT-IT result; (a) positive QFT-IT and (b) negative QFT-IT. The solid line represents the median value of IFN-γ levels at the two time points. The differences between the median values in each group before and after H treatment are significant by the Wilconxon’s signed rank test ( and , resp.). IFN-γ: interferon-gamma; H: isoniazid; QFT-IT: QuantiFERON-TB Gold in Tube.