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Pulmonary Medicine
Volume 2012, Article ID 816541, 9 pages
Review Article

Imaging Diagnosis of Interstitial Pneumonia with Emphysema (Combined Pulmonary Fibrosis and Emphysema)

1Department of Diagnostic Radiology, Saitama International Medical Center, Saitama Medical University, Hidaka, Saitama 350-1298, Japan
2Department of Respiratory Medicine, Saitama Medical University, Moroyama-Machi, Saitama 350-0040, Japan
3Department of Respiratory Medicine, Kanagawa Prefectural Cardiovascular and Respiratory Disease Center, Yokohama 236-0051, Japan
4Department of Radiology, Tsukuba Memorial Hospital, Tsukuba 300-2622, Japan
5Department of Pathology, Japanese Red Cross Medical Center, Tokyo 150-8935, Japan

Received 23 June 2011; Accepted 23 October 2011

Academic Editor: Masahito Ebina

Copyright © 2012 Fumikazu Sakai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Based on clinical and radiological findings, Cottin defined combined pulmonary fibrosis and emphysema (CPFE) as pulmonary emphysema in the upper lungs and interstitial pneumonia in the lower lungs with various radiological patterns. Pathologic findings of CPFE probably corresponded with diffuse interstitial pneumonia with pulmonary emphysema, emphysema with fibrosis, and the combination of both. We described reported radiological findings of CPFE.