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Pulmonary Medicine
Volume 2012, Article ID 854652, 9 pages
Research Article

Predicted Aerobic Capacity of Asthmatic Children: A Research Study from Clinical Origin

Centre for Child and Adolescent Health, Section of Aetiological Epidemiology, School of Social and Community Medicine, Faculty of Medicine and Dentistry, University of Bristol, Bristol BS8 2BN, UK

Received 22 December 2011; Revised 20 March 2012; Accepted 18 April 2012

Academic Editor: Luke Howard

Copyright © 2012 Lene Lochte. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To compare longitudinally PAC of asthmatic children against that of healthy controls during ten months. Methods. Twenty-eight asthmatic children aged 7–15 years and 27 matched controls each performed six submaximal exercise tests on treadmill, which included a test of EIA (exercise-induced asthma). Predicted aerobic capacity (mLO2/min/kg) was calculated. Spirometry and development were measured. Physical activity, medication, and “ever asthma/current asthma” were reported by questionnaire. Results. Predicted aerobic capacity of asthmatics was lower than that of controls ( 𝑃 = 0 . 0 0 1 5 ) across observation times and for both groups an important increase in predicted aerobic capacity according to time was observed ( 𝑃 < 0 . 0 0 1 ). FEV1 of the asthmatic children was within normal range. The majority (86%) of the asthmatics reported pulmonary symptoms to accompany their physical activity. Physical activity (hours per week) showed important effects for the variation in predicted aerobic capacity at baseline ( 𝐹 = 2 . 2 8 , 𝑃 = 0 . 0 6 1 ) and at the T4 observation ( 𝐹 = 3 . 0 3 , 𝑃 = 0 . 0 2 7 ) and the analyses showed important asthma/control group effects at baseline, month four, and month ten. Physical activity of the asthmatics correlated positively with predicted aerobic capacity. Conclusion. The asthmatic children had consistently low PAC when observed across time. Physical activity was positively associated with PAC in the asthmatics.