Loss of Asthma Control in Pediatric Patients after Discontinuation of Long-Acting Beta-Agonists

Table 2

Patient characteristics comparing those that maintained asthma control off LABA therapy at followup (controlled) and those that experienced loss of asthma control (uncontrolled). ^*represents 𝑃<0.05.

	Controlled	Uncontrolled
Patients, n	34	20
Time to f/u, weeks	10.3	11.5
Age, yr	11.3	10.2
Male sex (%)	22 (65)	11 (55)
Caucasian (%)	27 (79)	16 (80)
Insurance, government (%)	7 (21)	8 (40)
Smoke exposure, negative (%)	19 (56)	14 (70)
Atopy (%)	27 (79)	15 (75)
Duration of asthma, yr	7.6	6.4
LTRA use (%)	15 (44)	10 (50)
ACT, baseline	23.5	23.4
FVC, baseline % pred	105±11.6	104±12.1
FEV1, baseline % pred	102±11.8	100±10.5
FEF25-75, baseline	101±22.2	93±28.7
Change ACT	−0.5±4.1	−3.2±3.9^∗
Change FEV1, % pred	−1.9±11.0	−8.0±8.5^∗
Change FEF25-75, % pred	−10.8±16.4	−16.9±13.8
TLC, %	105.9±22.0	100.4±11.2
RV/TLC	0.22±0.07	0.31±0.09^∗
eNO	23.8±25.6	26.7±25.8
Exacerbation	0	2
Hospitalization	0	0