Pulmonary Medicine / 2013 / Article / Tab 1

Research Article

The Immediate Pulmonary Disease Pattern following Exposure to High Concentrations of Chlorine Gas

Table 1

Comparison of different criteria for classification of pulmonary disease patterns.

Pulmonary disease pattern2003 Mannino et al. guidelines [16]2005 ATS/ERS task force guidelines# [15]Graniteville criteria

ObstructiveMild:
 FEV1/FVC ratio < 70%,
 FEV1 ≥ 80% of predicted
Moderate:
 FEV1/FVC ratio < 70%,
 FEV1 ≥ 50% but < 80% of predicted
Severe:
 FEV1/FVC ratio < 70%,
 FEV1 < 50% of predicted
FEV1/VC ratio below LLN*FEV1/FVC ratio ≤ 0.70 and normal, reduced, or increased FEV1 and FVC percent predicted

RestrictiveFEV1/FVC ratio ≥ 70 and
FVC < 80% of predicted
TLC below LLN or
FEV1/VC ratio ≥ 85 and
a reduced VC
FEV1/FVC ratio ≥ 0.75,
FEV1 and FVC < 75%
of predicted

MixedNo criteria reportedFEV1/VC ratio and
TLC below LLN
FEV1/FVC ratio > 0.70 and < 0.75 and both FEV1 and FVC < 75% predicted

Vital capacity (VC) measures were unavailable, so we used FEV1/FVC ratio instead of FEV1/VC ratio as suggested by 2005 ATS/ERS guidelines.
*Lower limit of normal.

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