|
Investigator | Number of patients | Methods of diagnosis for OSA | Control group | Risk factor adjustments | Results |
|
Guilleminault et al. (1983) [6] | 400 | PSG | No | N/A | Cardiac arrhythmias observed in 48% of patients with OSA |
Mooe et al. (1996) [14] | 121 | PSG | Yes | Age. | Risk of AF after CABG in OSA patients, OR 2.8 (1.2–6.8) |
Mehra et al. (2006) [8] | 566 | PSG | Yes | Age, gender, BMI, coronary heart disease. | Risk of AF in OSA patients, adjusted OR 4.02 (1.03–15.74) |
Tanigawa et al. (2006) [9] | 1763 | Pulse oximeter during sleep | Yes | Age, BMI, alcohol intake, blood pressure, hypertension, and antihypertensives. | Risk of AF for severe OSA, adjusted OR 5.66 (1.75–18.34) |
Gami et al. (2007) [11] | 3542 | PSG | Yes | Age, gender, coronary artery disease, BMI. | Incident AF in OSA for patients age <65, HR 3.29 (1.35–8.04) |
Monahan et al. (2009) [10] | 2816 | PSG | Yes | Subjects serve as their own controls during event-free periods. | Risk of AF after a respiratory disturbance compared to normal breathing, OR 17.9 (2.2–144.2) |
Mehra et al. (2009) [15] | 2911 | PSG | Yes | Age, race, BMI, HTN, DM, CAD, pacemaker, cholesterol. | Increasing OSA quartile associated with CVE () but not AF. |
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