Flow-Volume Parameters in COPD Related to Extended Measurements of Lung Volume, Diffusion, and Resistance

Figure 2

DLCO_SB%p (a), VA%p (b), and DLCO_SB/VA%p (c) measured by single breath helium dilution with CO-diffusion in controls (healthy smokers) and COPD patients with GOLD stage 1–4. *Significant difference compared to healthy smokers, ^†significant difference compared to GOLD1, ^‡significant difference compared to GOLD2, ^#significant difference compared to GOLD3, one symbol flagging 𝑃<0.05, two symbols flagging 𝑃<0.01, and three symbols flagging 𝑃<0.001. Data are presented as individual dots together with median with interquartile range.

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