Hemoglobin Variant (Hemoglobin Aalborg) Mimicking Interstitial Pulmonary Disease

Table 2

Oxygen saturation, measured by pulse oximetry (s_pO₂), and results from arterial blood gas analyses: arterial oxygen saturation (SaO₂), partial pressure of oxygen (PaO₂), oxygen tension at 50% saturated hemoglobin (P50), and hemoglobin, functional hemoglobin, and lactate concentration before and after 6-minute walking test in 7 patients with Hb Aalborg.

	Patient 1 (woman)	Patient 2 (man)	Patient 3 (woman)	Patient 4 (woman)	Patient 5 (woman)	Patient 6 (man)	Index person
Before exercise
spO2 (%)	83	79	85	73	85	69	87
SaO2 (%)	83.3	79	85.5	73.2	85	69.4	87.3
PaO2 (mmHg)	91.5	89.25	90.75	81	114.8	100.5	102.75
P50 (mmHg)	59.6	56.85	50.63	45.23	69.68	77.25	54.9
Hemoglobin (g/dL)	0.73	0.82	0.78	0.72	0.65	0.74	0.75
Functional hemoglobin (g/dL)	0.69	0.76	0.74	0.68	0.63	0.71	0.71
Carboxyhemoglobin (g/dL)	0.0037	0.0051	0.003	0.003	0.0015	0.005	0.0033
Lactate (μg/dL)	8.11	8.11	5.41	5.41	15.3	9.91	9.91
After exercise
spO2 (%)	87	81	81	83	85	83	83
SaO2 (%)	87.5	81.7	81.5	83.2	85	83	82.9
PaO2 (mmHg)	91.5	96	93.75	102.75	91.5	112.5	96.75
P50 (mmHg)	47.85	58.8	57.9	61.28	51.68	68.85	54.23
Hemoglobin (g/dL)	0.73	0.82	0.78	0.74	0.69	0.74	0.77
Functional hemoglobin (g/dL)	0.69	0.77	0.74	0.70	0.62	0.72	0.73
Carboxyhemoglobin (g/dL)	0.0037	0.0043	0.0028	0.0036	0.003	0.0043	0.003
Lactate (μg/dL)	15.32	8.11	6.31	9.91	7.21	9.91	9