Review Article

Surgical and Bronchoscopic Lung Volume Reduction in Chronic Obstructive Pulmonary Disease

Table 1

Patient characterization for LVRS (adapted with modification [32]).

Indication (non-high-risk, better outcome chance)Contraindication (high-risk)

(1) Age <75 years 
(2) Marked dyspnea; MRC score >3 
(3) Severe emphysema: hyperinflation: TLC >125% of predicted, RV/TLC >0.65, and FEV1 <35% of predicted 
(4) Upper-lobe predominant emphysema (ULP) with low exercise capacity
(1) Severe parenchymal loss with DLCO <20% of predicted  
(2) FEV1 <20% 
(3) Pulmonary hypertension; mean pulmonary artery wedge pressure >35 
(4) Coronary artery disease.
(5) Homogenously [33] distributed emphysema