A Simple Clinical Measure of Quadriceps Muscle Strength Identifies Responders to Pulmonary Rehabilitation

Table 3

Binary logistic regression models for a responder in the six-minute walk distance (6MWD).

(a) Binary logistic regression analysis—responders defined as ≥25 m increase in 6MWD

	𝛽	SE	Wald 𝜒^2	P	Odds ratio (Exp 𝛽)	95% CI for Exp 𝛽
Univariate analysis
Quadriceps strength	−0.023	0.011	4.737	0.030	0.977	0.957–0.998
COPD self-efficacy score	0.565	0.304	3.450	0.063	1.760	0.969–3.196
Multivariate analysis
Quadriceps strength	−0.024	0.011	4.822	0.028	0.976	0.955–0.997
COPD self-efficacy score	0.626	0.313	4.015	0.045	1.871	1.014–3.451

(b) Binary logistic regression analysis—responders defined as ≥61.9 m increase in 6MWD

	𝛽	SE	Wald 𝜒^2	P	Odds ratio (Exp 𝛽)	95% CI for Exp 𝛽
Univariate analysis
Quadriceps strength	−0.048	0.017	8.291	0.004	0.953	0.922–0.985
Metabolic disease	−1.631	0.554	8.673	0.003	0.196	0.066–0.580
Musculoskeletal disease	−1.164	0.539	4.666	0.031	0.312	0.109–0.898
Baseline 6MWD	−0.006	0.003	4.592	0.032	0.994	0.989–1.000
Multivariate analysis
Quadriceps strength	−0.043	0.018	5.776	0.016	0.958	0.924–0.992
Metabolic disease	−1.762	0.648	7.391	0.007	0.172	0.048–0.612
Baseline 6MWD	−0.006	0.003	3.008	0.083	0.994	0.988–1.001

Only variables with 𝑃<0.1 are shown in the table.