Differences between Risk Factors Associated with Tuberculosis Treatment Abandonment and Mortality

Table 2

Univariate and multivariate analyses of risk factors associated with TB treatment abandonment.

Characteristics	Abandonment				Univariate		Multivariate
	Yes	(%)	No	(%)	OR (95% CI)		OR (95% CI)
Age
<40 years	52	(62.7)	621	(53.8)	1.0
>40 years	31	(37.3)	534	(46.2)	0.69 (0.43–1.12)	ns
Gender
Female	15	(17.9)	374	(31.9)	1.0
Male	69	(82.1)	799	(68.1)	2.15 (1.18–3.98)	0.007	2.05 (1.15–3.65)	0.015
HIV coinfection
No	76	(90.5)	1064	(90.7)	1.0
Yes	8	(9.5)	109	(9.3)	1.03 (0.45–2.27)	ns
Alcoholic
No	68	(81.0)	1054	(89.9)	1.0
Yes	16	(19.0)	119	(10.1)	2.08 (1.12–3.83)	0.011	—	ns
Literacy
Yes	62	(73.8)	881	(75.1)	1.0
No	22	(26.2)	292	(24.9)	1.07 (0.63–1.82)	ns
Treatment in the same city of residence
Yes	70	(83.3)	1010	(86.1)	1.0
No	14	(16.7)	163	(13.9)	1.24 (0.65–2.32)	ns
Area
Countryside	8	(9.5)	142	(12.1)	1.0
Urban area	76	(90.5)	1031	(87.9)	1.31 (0.60–2.99)	ns
Institutionalized
No	80	(95.2)	1124	(95.8)	1.0
Yes	4	(4.8)	49	(4.2)	1.15 (0.34–3.42)	ns
Extrapulmonary TB
No	78	(92.9)	942	(80.3)	1.0
Yes	6	(7.1)	231	(19.7)	0.31 (0.12–0.76)	0.005	0.33 (0.14–0.76)	0.010
Severe extrapulmonary TB
No	83	(98.8)	1103	(94.0)	1.0
Yes	1	(1.2)	70	(6.0)	0.19 (0.00–1.12)	ns
Diabetes
No	83	(98.8)	1095	(93.4)	1.0
Yes	1	(1.2)	78	(6.6)	0.17 (0.00–0.99)	0.046	—	ns
Cigarette smoking
No	76	(90.5)	1089	(92.8)	1.0
Yes	8	(9.5)	84	(7.2)	1.36 (0.59–3.05)	ns
Comorbidity
No	81	(96.4)	1047	(89.3)	1.0
Yes	3	(3.6)	126	(10.7)	0.31 (0.06–0.96)	0.036	—	ns
Treatment after relapse
No	81	(96.4)	1107	(94.4)	1.0
Yes	3	(3.6)	66	(5.6)	0.62 (0.12–1.97)	ns
Treatment after abandonment
No	64	(76.2)	1087	(92.7)	1.0
Yes	20	(23.8)	86	(7.3)	3.95 (2.20–7.05)	<0.001	3.41 (1.96–5.96)	<0.001

Meningitis, miliary, pericarditis, peritonitis, bilateral or extensive pleural effusion, spinal, genitourinary, and intestinal types.
ns: not significant.