Correlation between Clinical Characteristics and Chest Computed Tomography Findings of Pulmonary Cryptococcosis
Table 1
Clinical characteristics of 16 patients with pulmonary cryptococcosis.
Characteristics
Number of patients
16 (100.0%)
Male/female
10 (62.5%)/6 (37.5%)
Age (years)
60 [25–82]
<70 years/≥70 years
8 (50.0%)/8 (50.0%)
Host status
Immunocompetent
3 (18.8%)
Immunocompromised
13 (81.2%)
BMI, kg/m2
20.8 [16.0–28.3]
<18.5, 18.5~25, ≥25 kg/m2
1 (6.3%)/12 (75.0%)/3 (18.7%)
HbA1c (%)
5.6 [4.9–7.0]
≥6.5%/<6.5%
2 (12.5%)/14 (87.5%)
Symptoms
None
6 (37.5%)
Fever
5 (31.3%)
Cough
5 (31.3%)
General fatigue
3 (18.8%)
Dissemination/confined to the lung
1 (6.3%)/15 (93.7%)
Treatment and follow-up
No treatment
4 (25.0%)
Antifungal drugs
10 (62.5%)
Surgery + antifungal drugs
1 (6.3%)
Unknown
1 (6.3%)
Laboratory data
Median [range]
WBC (/μL)
8100 [1500–31400]
Lym (/μL)
1300 [230–2900]
Hb (g/dL)
11.3 [4.4–16.5]
Plt (×104/μL)
18.0 [1.4–36.0]
Albumin (g/dL)
3.8 [3.2–4.1]
ESR (mm/hr)
27 [1–78]
CRP (mg/dL)
0.7 [0.1–7.0]
IgG (mg/dL)
889 [410–4121]
Positive for serum cryptococcal antigen titer
16 (100%)
Diagnosis by
TBLB (histology)
4 (25.0%)
Surgery (histology)
1 (6.3%)
Bronchial brushing and washing (cytology)
2 (12.5%)
Positive of the serum cryptococcal antigen titer and radiological abnormalities
9 (56.3%)
Values are shown as median [range] or number (%). BMI: body mass index, HbA1c: hemoglobin A1c, WBC: white blood cell, Lym: lymphocyte cell, Hb: hemoglobin, Plt: platelet, ESR: erythrocyte sedimentation rate, CRP: C-reactive protein, IgG: immunoglobulin G, and TBLB: transbronchial lung biopsy.
